fnctId=prof,fnctNo=216 Mingeun Kim LAB MAJOR/RESEARCH TEL (062)530-3376 EMAIL mingeunkim@chonnam.ac.kr HOME - Major & Degree Bioinorganic Chemistry Ph.D., Department of Chemistry, KAIST (Advisor: Professor Mi Hee Lim) Education 2019.02 – 2022. 08 Ph.D., Department of Chemistry, KAIST (Advisor: Professor Mi Hee Lim) 2017.03 – 2019. 02 M.S., Department of Chemistry, UNIST (Advisor: Professor Mi Hee Lim) 2011.03 – 2017. 02 B.S., Department of Chemistry, Pukyong National University Experience 2025.09 – Present Assistant Professor, Department of Chemistry, Chonnam National University 2023.07 – 2024.03 Visiting Investigator, Department of Pharmaceutical Sciences, University of Michigan (Advisor: Professor Anna Schwendeman) 2022.09 – 2025.08 Postdoctoral Fellow, Department of Chemistry, KAIST (Advisor: Professor Mi Hee Lim) Research Interest Metal–Protein Coordination Chemistry Fluorescent Chemosensors Pathology-regulation Molecules Chemical Drug Delivery Systems Representative Publications 11. Mingeun Kim, Yuxi Lin, Eunju Nam, Dong Min Kang, Sungsu Lim, Yun Kyung Kim, Young-Ho Lee,* Mi Hee Lim* “Interactions with Tau’s Microtubule-Binding Repeats Modulate Amyloid-β Aggregation and Toxicity” Nat. Chem. Biol. 2025, DOI: 10.1038/s41589-025-01987-0. 10. Jeasang Yoo, Jong-Min Suh, Gunhee Kim, Hélène Bernard, Raphaël Tripier, Dongwook Kim, Mingeun Kim,* Mi Hee Lim* “Cobalt Complexes as Modulators against Aβ Aggregation and Toxicity” J. Inorg. Biochem. 2025, 271, 112972 (*Co-corresponding Authors). 9. Chanju Na,† Mingeun Kim,† Gunhee Kim, Yuxi Lin, Young-Ho Lee, Wojciech Bal,* Eunju Nam,* Mi Hee Lim* “Distinct Aggregation Behavior of N-Terminally Truncated Aβ4-42 over Aβ1-42 in the Presence of Zn(II)” ACS Chem. Neurosci. 2025, 16, 732-744 (†Co-first Authors). 8. Mingeun Kim, Gajendra Gupta,* Junseong Lee, Chanju Na, Jimin Kwak, Yuxi Lin, Young-Ho Lee, Mi Hee Lim,* Chang Yeon Lee* “Metal-BODIPY Complexes: Versatile Photosensitizers for Oxidizing Amyloid-β Peptides and Modulating Their Aggregation Profiles” Inorg. Chem. Front. 2024, 11, 1966-1977. 7. Seongmin Park,† Mingeun Kim,† Yuxi Lin, Mannkyu Hong, Geewoo Nam, Adam Mieczkowski, József Kardos, Young-Ho Lee,* Mi Hee Lim* “Designing Multi-Target-Directed Flavonoids: A Strategic Approach to Alzheimer’s Disease” Chem. Sci. 2023, 14, 9293-9305 (†Co-first Authors). 6. Jong-Min Suh,† Mingeun Kim,† Jeasang Yoo, Jiyeon Han, Cinthya Paulina, Mi Hee Lim* “Intercommunication between Metal Ions and Amyloidogenic Peptides or Proteins in Protein Misfolding Disorders” Coord. Chem. Rev. 2023, 478, 214978 (†Co-first Authors). 5. Mannkyu Hong,† Mingeun Kim,† Jiwon Yoon, Seung-Hee Lee,* Mu-Hyun Baik,* Mi Hee Lim* “Excited-State Intramolecular Hydrogen Transfer of Compact Molecules Controls Amyloid Aggregation Profiles” JACS Au 2022, 2, 2001-2012 (†Co-first Authors). 4. Mingeun Kim, Mi Hee Lim* “Redox Properties of Small Molecules Essential for Multiple Reactivities with Pathological Factors in Alzheimer’s Disease” Bull. Korean. Chem. Soc. 2021, 42, 1272-1280. 3. Mingeun Kim,† Min Hee Park,† Geewoo Nam, Misun Lee, Juhye Kang, Im-Sook Song, Min-Koo Choi, Hee Kyung Jin,* Jae-sung Bae,* Mi Hee Lim* “A Glycosylated Prodrug to Attenuate Neuroinflammation and Improve Cognitive Deficits in Alzheimer’s Disease Transgenic Mice” Mol. Pharmaceutics 2021, 18, 101-112 (†Co-first Authors). 2. Mingeun Kim,† Juhye Kang,† Misun Lee,† Jiyeon Han, Geewoo Nam, Eunyoung Tak, Min Sun Kim, Hyuck Jin Lee, Eunju Nam, Jiyong Park, Soo Jin Oh, Ji-Yoon Lee, Joo-Yong Lee,* Mu-Hyun Baik,* Mi Hee Lim* “Minimalistic Principles for Designing Small Molecules with Multiple Reactivities against Pathological Factors in Dementia” J. Am. Chem. Soc. 2020, 142, 8183-8193 (†Co-first Authors). 1. Misun Lee,† Mingeun Kim,† Anjong Florence Tikum,† Hyuck Jin Lee, Vijayan Thamilarasan, Mi Hee Lim,* Jinheung Kim* “A Near-Infrared Fluorescent Probe for Amyloid-β Aggregates” Dyes Pigment. 2019, 162, 97-103 (†Co-first Authors).